Analysis of serum alpha-fetoprotein (AFP) and AFP-L3 levels by protein microarray
نویسندگان
چکیده
منابع مشابه
Status of serum alpha feto-protein (AFP) and midkine (MDK) levels in patients with hepatocellular carcinoma
Introduction: Hepatocellular carcinoma (HCC) is sixth common cancers worldwide and predominant in Asia and Africa. A number of evidence suggests a possible role of midkine (MDK) and α-fetoprotein (AFP) in the pathogenesis of hepatocellular carcinoma (HCC). Materials and methods: We studied MDK and AFP in patients with HCC or in healthy controls. MDK and AFP was measured by enzyme linked immuno...
متن کاملLevels of maternal serum alpha-fetoprotein (AFP) in pregnant women and subsequent breast cancer risk.
High maternal serum alpha-fetoprotein (AFP) levels during pregnancy may be instrumental in reducing the subsequent risk of breast cancer. This hypothesis was tested in a nested case-control study using stored frozen sera accrued between 1959 and 1966 by the University of California at Berkeley Child Health and Development Studies (CHDS) group from a cohort of pregnant women. Cases with histolog...
متن کاملAlpha-fetoprotein (AFP) and Chromosomal/Genetic Instability Disorders: Is AFP a Reporter Protein for DNA Damage-Sensing and Repair?
Many cancer cells exhibit an unstable genome resulting from chromosomal aberrations and gene mutations in somatic cells which generate heterogeneous cell populations manifesting diseases such as cancer. Genomic/chromosomal instability can arise from non-repaired broken DNA along the chromosome or from loss of telomeric ends of chromosomes. Normally, DNA single or double-stranded breaks are repa...
متن کاملNovel characteristics of alpha-fetoprotein (AFP)-producing gastric cancer
Background Although serum AFP level is increased in the AFP-producing gastric cancer (GC) patient, AFP-producing GC may become recurrent without re-elevation of serum AFP level. Therefore, novel characteristics of AFP-producing GC such as other biomarkers are to be explored. Results 35 AFP-GC and 48 non-AFP-GC patients were included. Our present study revealed that blood type O (15 cases, 42....
متن کاملAFP (alpha fetoprotein): who are you in gastrology?
AFP-producing (hepatoid differentiation) gastric cancer (GC) initially reported in 1970 plays an important role in the field of gastrology, which should be distinguished from other solid-type GCs owing to their different biological behavior. This review article aims to summarize the literature related to the role of AFP in gastric cancer and to unveil the underlying mechanism by which AFP-produ...
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ژورنال
عنوان ژورنال: Journal of International Medical Research
سال: 2018
ISSN: 0300-0605,1473-2300
DOI: 10.1177/0300060518789304